Charles Sylvia Jr., DVM, MS

Experience

• 15 years of experience in veterinary anesthesia, surgical, clinical and research disciplines.
• Accomplished surgeon with extensive experience in cardiothoracic, general surgery and interventional procedures. Experienced in cardiopulmonary bypass procedures.
• Medical Device and Animal Model expertise
  • Cardiothoracic and vascular surgery for devices such as grafts, cardiac assist systems, heart valves, infarction, etc.
  • Catheter studies: vascular access, stents, ablation devices, TAVR, renal denervation, thrombectomy, Interventional cardiology, models of thrombosis and anti-thrombogenic or antimicrobial coating studies.
  • Arterial and venous closure devices.
  • Bleeding, hemostasis, and shock models.
  • GI studies, Neurostimulators and laparoscopic devices.
• FDA and OECD regulatory guidelines
  • 20 years of experience as a Study Director for GLP and non-GLP studies. Over 75 reports have been submitted to the FDA for regulatory clearance via 510k or IDE.
  • Knowledgeable with ISO standards (e.g. ISO-10993)

Education

• DVM from the UC Davis School of Veterinary Medicine. Residency at Stanford University. Master’s Degree in Physiology. Bachelor’s degree in Animal Sciences.

Taylor Spangler, DVM, DACVP

Dr. Taylor Spangler is a board-certified veterinary pathologist with over 20 years of experience in preclinical medical device research and diagnostic pathology. As Senior Research Pathologist at Bayside Preclinical Services, Dr. Spangler provides expert consultation in gross and histopathological evaluations, supporting FDA submissions for a wide range of medical devices.

Dr. Spangler’s expertise is rooted in gross necropsy, having personally performed thousands of postmortem examinations throughout his career. He believes that continuity in pathology evaluation is key to high-quality outcomes. With direct oversight of tissue trimming and histology preparation, combined with personal histopathology evaluation and authorship of the final pathology report, Dr. Spangler ensures that findings are thorough, cohesive, and accurately represented. This approach enhances consistency, captures relevant pathology, and supports stronger, more defensible study results.

Throughout his career, Dr. Spangler has contributed to hundreds of GLP preclinical studies, with expertise spanning cardiovascular, neurovascular, structural heart, thrombectomy, vascular closure, and a variety of implantable and interventional devices. His extensive background includes cause-of-death evaluations, diagnostic biopsy interpretation, and comprehensive pathology support for regulatory submissions.

Dr. Spangler earned his DVM from the University of Illinois and completed his residency in anatomic pathology at the University of California, Davis. He became a Diplomate of the American College of Veterinary Pathologists in 2005.

Experience : 

• Over 15 years of gross necropsy and histopathology consultation for preclinical medical device studies in support of 510k, IDE, R&D, etc.
• Performed over 1000 diagnostic and research oriented veterinary necropsies.
• On site consultation and necropsy services provided at over 12 different CROs and research facilities nationwide.
• Produced over 200 comprehensive GLP pathology reports.

Education : 

• BS in Animal Physiology from UC San Diego, 1994
• DVM at University of Illinois at Urbana-Champaign, 2000
• Anatomic veterinary pathology residency at UC Davis, 2005
• Board certification, American College of Veterinary Pathology, 2005

Kristina Vu, DVM, DACVP